Article
Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy.
European journal of human genetics : EJHG - 1 Jun 2010
Bouzigon Emmanuelle, Forabosco Paola, Koppelman Gerard H, Cookson William O C M, Dizier Marie-Hélène, Duffy David L, Evans David M, Ferreira Manuel A R, Kere Juha, Laitinen Tarja, Malerba Giovanni, Meyers Deborah A, Moffatt Miriam, Martin Nicholas G, Ng Mandy Y, Pignatti Pier Franco, Wjst Mathias, Kauffmann Francine, Demenais Florence, Lewis Cathryn M
Abstract excerpt
Asthma is caused by a heterogeneous combination of environmental and genetic factors. In the context of GA2LEN (Global Allergy and Asthma European Network), we carried out meta-analyses of almost all genome-wide linkage screens conducted to date in 20 independent populations from different ethnic origins (>or=3024 families with >or=10 027 subjects) for asthma, atopic asthma, bronchial hyper-responsiveness and...
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