Article
Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families.
Human molecular genetics - 15 Dec 2004
Bouzigon Emmanuelle, Dizier Marie-Hélène, Krähenbühl Christine, Lemainque Arnaud, Annesi-Maesano Isabella, Betard Christine, Bousquet Jean, Charpin Denis, Gormand Frédéric, Guilloud-Bataille Michel, Just Jocelyne, Le Moual Nicole, Maccario Jean, Matran Régis, Neukirch Françoise, Oryszczyn Marie-Pierre, Paty Evelyne, Pin Isabelle, Rosenberg-Bourgin Myriam, Vervloet Daniel, Kauffmann Francine, Lathrop Mark, Demenais Florence
Abstract excerpt
A genome-wide scan for asthma phenotypes was conducted in the whole sample of 295 EGEA families selected through at least one asthmatic subject. In addition to asthma, seven phenotypes involved in the main asthma physiopathological pathways were considered: SPT (positive skin prick test response to at least one of 11 allergens), SPTQ score being the number of positive skin test responses to 11 allergens,...
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