Article
Quantitative linkage genome scan for atopy in a large collection of Caucasian families.
Human genetics - 1 Mar 2007
Webb Bradley T, van den Oord Edwin, Akkari Anthony, Wilton Steve, Ly Tina, Duff Rachael, Barnes Kathleen C, Carlsen Karin, Gerritsen Jorrit, Lenney Warren, Silverman Michael, Sly Peter, Sundy John, Tsanakas John, von Berg Andrea, Whyte Moira, Blumenthal Malcolm, Vestbo Jorgen, Middleton Lefkos, Helms Peter J, Anderson Wayne H, Pillai Sreekumar G
Abstract excerpt
Quantitative phenotypes correlated with a complex disorder offer increased power to detect linkage in comparison to affected-unaffected classifications. Asthma is a complex disorder characterized by periods of bronchial obstruction and increased bronchial hyper reactivity. In childhood and early adulthood, asthma is frequently associated also with quantitative measures of atopy. Genome wide quantitative...
Topics
- Adolescent
- Adult
- Animals
- Asthma
- Child
- Child, Preschool
- Family
- Female
- Genetic Linkage
- Genetic Predisposition to Disease