Article
Susceptibility genes in asthma and allergy.
Current allergy and asthma reports - 1 Mar 2001
Ober C
Abstract excerpt
Genome-wide screens for asthma and atopy susceptibility loci have been completed in six population samples. Despite the extensive clinical heterogeneity associated with these phenotypes, 20 chromosomal regions show evidence of linkage (P < 0.01) in three or more population samples. Thus, this survey suggests that at least 20 independent loci influence susceptibility to asthma, atopy, or associated phenotypes and...
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