Article
Meta-analysis of genome-wide linkage studies of asthma and related traits.
Respiratory research - 28 Apr 2008
Denham Samuel, Koppelman Gerard H, Blakey John, Wjst Matthias, Ferreira Manuel A, Hall Ian P, Sayers Ian
Abstract excerpt
BACKGROUND: Asthma and allergy are complex multifactorial disorders, with both genetic and environmental components determining disease expression. The use of molecular genetics holds great promise for the identification of novel drug targets for the treatment of asthma and allergy. Genome-wide linkage studies have identified a number of potential disease susceptibility loci but replication remains inconsistent....
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