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Article

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

Nature genetics - 1 Jun 2018

Zhu Zhaozhong, Lee Phil H, Chaffin Mark D, Chung Wonil, Loh Po-Ru, Lu Quan, Christiani David C, Liang Liming

Abstract excerpt

Clinical and epidemiological data suggest that asthma and allergic diseases are associated and may share a common genetic etiology. We analyzed genome-wide SNP data for asthma and allergic diseases in 33,593 cases and 76,768 controls of European ancestry from UK Biobank. Two publicly available independent genome-wide association studies were used for replication. We have found a strong genome-wide genetic...

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Identifiers

PMID: 29785011
DOI: 10.1038/s41588-018-0121-0
PMCID: PMC5980765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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