Article
Genome-wide search for atopy susceptibility genes in Dutch families with asthma.
The Journal of allergy and clinical immunology - 1 Mar 2002
Koppelman Gerard H, Stine O Colin, Xu Jianfeng, Howard Timothy D, Zheng Siqun L, Kauffman Henk F, Bleecker Eugene R, Meyers Deborah A, Postma Dirkje S
Abstract excerpt
BACKGROUND: Atopy is a phenotype associated with asthma that has a heritable component. However, the role of atopysusceptibility genes in the development and expression of asthma and allergic disorders is not understood. OBJECTIVE: We sought to study the familial aggregation and co-occurrence of atopic phenotypes within family members of patients with asthma and to identify chromosomal regions that may contain...
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