Genome-wide search for atopy susceptibility genes in Dutch families with asthma.

doi:10.1067/mai.2002.122235

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Article

Genome-wide search for atopy susceptibility genes in Dutch families with asthma.

The Journal of allergy and clinical immunology - 1 Mar 2002

Koppelman Gerard H, Stine O Colin, Xu Jianfeng, Howard Timothy D, Zheng Siqun L, Kauffman Henk F, Bleecker Eugene R, Meyers Deborah A, Postma Dirkje S

Abstract excerpt

BACKGROUND: Atopy is a phenotype associated with asthma that has a heritable component. However, the role of atopysusceptibility genes in the development and expression of asthma and allergic disorders is not understood. OBJECTIVE: We sought to study the familial aggregation and co-occurrence of atopic phenotypes within family members of patients with asthma and to identify chromosomal regions that may contain...

Topics

Adolescent
Adult
Aged
Allergens
Asthma
Child
Chromosome Mapping
Chromosomes, Human
Eosinophils
Family
Female
Genetic Linkage
Genetic Predisposition to Disease
Genome

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hypersensitivity, Immediate

Immunoglobulin E

Male

Source

Open in PubMed

Identifiers

PMID: 11897998
DOI: 10.1067/mai.2002.122235

Provenance

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