Article
Cyclooxygenase-2 and n-6 PUFA are lower and DHA is higher in the cortex of fat-1 mice.
Neurochemistry international - 1 Mar 2010
Boudrault Cynthia, Bazinet Richard P, Kang Jing X, Ma David W L
Abstract excerpt
Neuroinflammation is believed to play an important role in neurological diseases such as Alzheimer's disease (AD). Growing evidence suggests that n-3 PUFA have protective effects by inhibiting inflammatory processes including synthesis of eicosanoids from arachidonic acid. There is also some evidence suggesting that inflammatory mediators associated with the arachidonic acid cascade may be modulated by n-3 PUFA...
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