Article
Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease.
Neurochemical research - 1 Mar 2010
Fraser Thomas, Tayler Hannah, Love Seth
Abstract excerpt
Dietary omega3-polyunsaturated fatty acids are thought to influence the risk of Alzheimer's disease (AD), and supplemental docosahexaenoic acid (DHA; 22:6n-3) has been reported to reduce neurodegeneration in mouse models of AD. We have analysed the fatty acid composition of frontal, temporal and parietal neocortex in 58 normal and 114 AD brains. Significant reductions were found for stearic acid (18:0) in frontal...
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