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Article

Establishing a role for the GTPase Ypt1p at the late Golgi.

Traffic (Copenhagen, Denmark) - 1 Apr 2010

Sclafani Anthony, Chen Shuliang, Rivera-Molina Felix, Reinisch Karin, Novick Peter, Ferro-Novick Susan

Abstract excerpt

GTPases of the Rab family cycle between an inactive (GDP-bound) and active (GTP-bound) conformation. The active form of the Rab regulates a variety of cellular functions via multiple effectors. Guanine nucleotide exchange factors (GEFs) activate Rabs by accelerating the exchange of GDP for GTP, while GTPase activating proteins (GAPs) inactivate Rabs by stimulating the hydrolysis of GTP. The GTPase Ypt1p is...

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Identifiers

PMID: 20059749
DOI: 10.1111/j.1600-0854.2010.01031.x
PMCID: PMC2861988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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