Article
The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/32.
Molecular biology of the cell - 1 Dec 2000
Jones S, Newman C, Liu F, Segev N
Abstract excerpt
In yeast, the Ypt1 GTPase is required for ER-to-cis-Golgi and cis-to-medial-Golgi protein transport, while Ypt31/32 are a functional pair of GTPases essential for exit from the trans-Golgi. We have previously identified a Ypt1 guanine nucleotide exchange factor (GEF) activity and characterized it as a large membrane-associated protein complex that localizes to the Golgi and can be extracted from the membrane by...
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