Article
Functional implications of genetic interactions between genes encoding small GTPases involved in vesicular transport in yeast.
Molecular & general genetics : MGG - 1 Feb 1999
Yoo J S, Grabowski R, Xing L, Trepte H H, Schmitt H D, Gallwitz D
Abstract excerpt
Ras-related, guanine nucleotide-binding proteins of the Ypt/Rab family play a key role at defined steps in vesicular transport, both in yeast and in mammalian cells. In yeast, Ypt1p has an essential function late in endoplasmic reticulum (ER) to Golgi transport, and the redundant Ypt31/Ypt32 GTPases have been proposed to act in transport through and/or from the Golgi. Here we report that mutant alleles of YPT31...
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