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Article

TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.

Nature cell biology - 1 Nov 2006

Morozova Nadya, Liang Yongheng, Tokarev Andrei A, Chen Shu H, Cox Randal, Andrejic Jelena, Lipatova Zhanna, Sciorra Vicki A, Emr Scott D, Segev Nava

Abstract excerpt

Ypt-Rab GTPases are key regulators of the various steps of intracellular trafficking. Guanine nucleotide-exchange factors (GEFs) regulate the conversion of Ypt-Rabs to the GTP-bound state, in which they interact with effectors that mediate all the known aspects of vesicular transport. An interesting possibility is that Ypt-Rabs coordinate separate steps of the transport pathways. The conserved modular complex...

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Identifiers

PMID: 17041589
DOI: 10.1038/ncb1489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.PMID 17041589Read ↗

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