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Article

Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes.

Toxicology and applied pharmacology - 15 Apr 2010

Huen Karen, Harley Kim, Bradman Asa, Eskenazi Brenda, Holland Nina

Abstract excerpt

The paraoxonase 1 (PON1) enzyme prevents low-density lipoprotein oxidation and also detoxifies the oxon derivatives of certain neurotoxic organophosphate (OP) pesticides. PON1 activity in infants is low compared to adults, rendering them with lower metabolic and antioxidant capacities. We made a longitudinal comparison of the role of genetic variability on control of PON1 phenotypes in Mexican-American mothers...

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Source

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Identifiers

PMID: 20045427
DOI: 10.1016/j.taap.2009.12.031
PMCID: PMC2846980

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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