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Article

Genetic polymorphisms and activity of PON1 in a Mexican population.

Toxicology and applied pharmacology - 15 Jun 2005

Rojas-García A E, Solís-Heredia M J, Piña-Guzmán B, Vega L, López-Carrillo L, Quintanilla-Vega B

Abstract excerpt

Human paraoxonase (PON1) plays a role in detoxification of organophosphorus (OP) compounds by hydrolyzing the bioactive oxons, and in reducing oxidative low-density lipoproteins, which may protect against atherosclerosis. Some PON1 polymorphisms have been found to be responsible for variations in catalytic activity and expression and have been associated with susceptibility to OP poisoning and vascular diseases....

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Source

Identifiers

PMID: 15922013
DOI: 10.1016/j.taap.2004.10.015

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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