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Article

Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children.

Environmental and molecular mutagenesis - 1 Mar 2011

Huen Karen, Barcellos Lisa, Beckman Kenneth, Rose Sherri, Eskenazi Brenda, Holland Nina

Abstract excerpt

Paraoxonase 1 (PON1) prevents oxidation of low-density lipoproteins and inactivates toxic oxon derivatives of organophosphate pesticides (OPs). More than 250 SNPs have been previously identified in the PON1 gene, yet studies of PON1 genetic variation focus primarily on a few promoter SNPs (-108, -162) and coding SNPs (192, 55). We sequenced the PON1 gene in 30 subjects from a Mexican-American birth cohort and...

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Source

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Identifiers

PMID: 20839225
DOI: 10.1002/em.20567
PMCID: PMC3003760

Genes

PON1
PON2
PON3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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