Article
Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides.
Toxicology letters - 24 Jul 2009
López-Flores I, Lacasaña M, Blanco-Muñoz J, Aguilar-Garduño C, Sanchez-Villegas P, Pérez-Méndez O A, Gamboa-Avila R
Abstract excerpt
Paraoxonase-1 (PON1) is a serum enzyme which catalyzes the hydrolysis of organophosphate pesticides. In this study we conducted a cross-sectional study and reported on the distribution of three common genetic polymorphisms of the PON1 gene in a population of floriculture workers from Mexico as well as the association between those polymorphisms and other predictors with serum PON1 activity on paraoxon, diazoxon...
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