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Article

Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women.

PloS one - 1 Jan 2011

Harley Kim G, Huen Karen, Aguilar Schall Raul, Holland Nina T, Bradman Asa, Barr Dana Boyd, Eskenazi Brenda

Abstract excerpt

BACKGROUND: Epidemiologic studies suggest that maternal organophosphorus (OP) pesticide exposure is associated with poorer fetal growth, but findings are inconsistent. We explored whether paraoxonase (PON1), a key enzyme involved in detoxification of OPs, could be an effect modifier in this assoc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21904599
DOI: 10.1371/journal.pone.0023923
PMCID: PMC3164135

Genes

PON1
DAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21904599-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women.PMID 21904599Read ↗

Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes.Semantic proximity Read ↗

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Prenatal exposure to organophosphate pesticides, maternal paraoxonase 1 genotype, and childhood neurodevelopment at 24 months of age in Shandong, China.Semantic proximity Read ↗

Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms.Semantic proximity Read ↗

Association between pesticide exposure and paraoxonase-1 (PON1) polymorphisms, and neurobehavioural outcomes in children: a systematic review.Semantic proximity Read ↗

Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community.Semantic proximity Read ↗

Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood.Semantic proximity Read ↗

Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children.Semantic proximity Read ↗

Increased influence of genetic variation on PON1 activity in neonates.Semantic proximity Read ↗

PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genesSemantic proximity Read ↗

Urinary organophosphate insecticide metabolite concentrations during pregnancy and children's interpersonal, communication, repetitive, and stereotypic behaviors at 8 years of age: The home study.Semantic proximity Read ↗

RETRACTED: Paraoxonase I polymorphisms and attention/hyperactivity in school-age children from Mexico City, Mexico.Semantic proximity Read ↗

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