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Article

[Cytogenetic and molecular genetic alterations on chromosome 4q in human hepatocellular carcinoma].

Ai zheng = Aizheng = Chinese journal of cancer - 1 Sept 2008

Zhang Hua-Kun, Wang Hui-Yun, Xia Jian-Chuan

Abstract excerpt

The carcinogenesis of hepatocellular carcinoma (HCC) is a multi-factor, multi-step, multi-gene and complicated process. Specific chromosome losses and corresponding inactivation of tumor suppressor genes (TSGs) are frequently detected during the development of HCC. A high frequency of loss on chromosome 4q in HCC has been reported, suggesting that the dysfunction of specific TSGs on this chromosome arm is...

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Share to Carcinoma, Hepatocellular
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 4

Share to Comparative Genomic Hybridization

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Share to In Situ Hybridization, Fluorescence

Share to Liver Neoplasms

Share to Loss of Heterozygosity

Source

Identifiers

PMID: 18799044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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