Article
Whole-genome profiling of chromosomal aberrations in hepatoblastoma using high-density single-nucleotide polymorphism genotyping microarrays.
Cancer science - 1 Mar 2008
Suzuki Makoto, Kato Motohiro, Yuyan Chen, Takita Junko, Sanada Masashi, Nannya Yasuhito, Yamamoto Go, Takahashi Atsushi, Ikeda Hitoshi, Kuwano Hiroyuki, Ogawa Seishi, Hayashi Yasuhide
Abstract excerpt
To identify the genomic profile and elucidate the pathogenesis of hepatoblastoma (HBL), the most common pediatric hepatic tumor, we performed high-density genome-wide single-nucleotide polymorphism (SNP) microarray analyses of 17 HBL samples. The copy number analyzer for GeneChip(R) (CNAG) and allele-specific copy number analysis using anonymous references (AsCNAR) algorithms enabled simple but sensitive...
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