Article
Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility.
Human genetics - 1 Mar 2010
Alter Andrea, de Léséleuc Louis, Van Thuc Nguyen, Thai Vu Hong, Huong Nguyen Thu, Ba Nguyen Ngoc, Cardoso Cynthia Chester, Grant Audrey Virginia, Abel Laurent, Moraes Milton Ozório, Alcaïs Alexandre, Schurr Erwin
Abstract excerpt
The chromosomal region 10p13 has been linked to paucibacillary leprosy in two independent studies. The MRC1 gene, encoding the human mannose receptor (MR), is located in the 10p13 region and non-synonymous SNPs in exon 7 of the gene have been suggested as leprosy susceptibility factors. We determ...
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