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Article

A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein.

Immunogenetics - 1 Jan 1994

Madsen H O, Garred P, Kurtzhals J A, Lamm L U, Ryder L P, Thiel S, Svejgaard A

Abstract excerpt

Human mannan-binding protein (MBP) is a serum lectin participating in the innate immune defence. Low MBP concentrations are explained by the dominant action of a point mutation at codon 54 of the MBP gene in Eskimos, partially in Caucasians, but not in Africans. A previously described point mutation at codon 57 was very frequent (0.23) in East Africans, low in Caucasians (0.02), and absent in Eskimos. The African...

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Source

Identifiers

PMID: 8206524
DOI: 10.1007/BF00163962

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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