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Article

Genetic variants in mannose receptor gene (MRC1) confer susceptibility to increased risk of sarcoidosis.

BMC medical genetics - 28 Oct 2010

Hattori Takeshi, Konno Satoshi, Takahashi Ayumu, Isada Akira, Shimizu Kaoruko, Shimizu Kenichi, Taniguchi Natsuko, Gao Peisong, Yamaguchi Etsuro, Hizawa Nobuyuki, Huang Shau-Ku, Nishimura Masaharu

Abstract excerpt

BACKGROUND: Mannose receptor (MR) is a member of the C-type lectin receptor family involved in pathogen molecular-pattern recognition and thought to be critical in shaping host immune response. The aim of this study was to investigate potential associations of genetic variants in the MRC1 gene with sarcoidosis. METHODS: Nine single nucleotide polymorphisms (SNPs), encompassing the MRC1 gene, were genotyped in a...

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Source

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Identifiers

PMID: 21029423
DOI: 10.1186/1471-2350-11-151
PMCID: PMC2987761

Genes

MRC1

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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