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Article

Detection of c-KIT and PDGFRA gene mutations in gastrointestinal stromal tumors: comparison of DHPLC and DNA sequencing methods using a single population-based cohort.

American journal of clinical pathology - 1 Jan 2010

Battochio Angeline, Mohammed Shamayel, Winthrop Debra, Lefresne Shilo, Mulder Karen, Chu Quincy, O'Hara Carolyn, Lai Raymond

Abstract excerpt

Mutational analysis of c-KIT or PDGFRA has become an important laboratory assay for patients with gastrointestinal stromal tumors (GISTs) because the results are useful in predicting the responsiveness to imatinib. To assess the diagnostic usefulness of denaturing high-pressure liquid chromatogra...

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Source

Identifiers

PMID: 20023271
DOI: 10.1309/AJCP1FNW7RGZFTYU

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20023271-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Detection of c-KIT and PDGFRA gene mutations in gastrointestinal stromal tumors: comparison of DHPLC and DNA sequencing methods using a single population-based cohort.PMID 20023271Read ↗

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