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Analysis of mutation of the c-Kit gene and PDGFRA in gastrointestinal stromal tumors

2 Jul 2015

Abstract excerpt

The aim of the present study was to investigate mutation status of the c‑kit gene (KIT) and PDGFRA in patients with a gastrointestinal stromal tumor (GIST). In total, 93 patients with a GIST were included in the study, in which polymerase chain reaction amplification and gene sequencing were used to detect the sequences of exons 9, 11, 13 and 17 in KIT and exons 12 and 18 in PDGFRA. KIT mutations were detected in...

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Identifiers

PMID: 26622437
DOI: 10.3892/etm.2015.2613

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