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Article

Tyrosine kinase mutations in gastrointestinal stromal tumors in a nation-wide study in Iceland.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Sept 2010

Tryggvason Geir, Hilmarsdottir Bylgja, Gunnarsson Guethmundur H, Jónsson Jón Jóhannes, Jónasson Jón G, Magnússon Magnús K

Abstract excerpt

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. It is characterized by activating mutations in the tyrosine kinase genes c-kit or PDGFRA. This study examined the mutation rate and type in a population-based material. All gastrointestinal m...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20718716
DOI: 10.1111/j.1600-0463.2010.02643.x

Genes

PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20718716-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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