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Article

Detection of KIT and PDGFRA mutations in the plasma of patients with gastrointestinal stromal tumor.

Targeted oncology - 1 Dec 2015

Kang Guhyun, Bae Byung Noe, Sohn Byeong Seok, Pyo Jung-Soo, Kang Gu Hyum, Kim Kyoung-Mee

Abstract excerpt

In subsets of gastrointestinal stromal tumors (GISTs), mutations of the KIT and PDGFRA receptor tyrosine kinases correlate with tumor prognosis and response to tyrosine kinase inhibitors (TKIs). Determining genotypes in TKI-resistant GISTs is challenging due to the potential risks and limitations of repeated biopsies during the course of treatment. We prospectively collected plasma samples from three GIST...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25735500
DOI: 10.1007/s11523-015-0361-1

Genes

KIT
PDGFRA
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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