Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detecting Primary KIT Mutations in Presurgical Plasma of Patients with Gastrointestinal Stromal Tumor.

Molecular diagnosis & therapy - 1 Aug 2016

Kang Guhyun, Sohn Byeong Seok, Pyo Jung-Soo, Kim Jung Yeon, Lee Boram, Kim Kyoung-Mee

Abstract excerpt

INTRODUCTION: Assessment of KIT/PDGFRA mutations is essential for therapeutic decision making in patients with gastrointestinal stromal tumor (GIST). Blood-derived circulating tumor DNA can provide molecular information representative of the tumor tissue. METHODS: In this study, primary tumors and matched presurgical blood samples were collected from 25 patients with localized gastric GIST, and the DNAs were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to DNA, Neoplasm

Share to Gastrointestinal Stromal Tumors

Share to Proto-Oncogene Proteins c-kit

Share to Tumor Burden

Source

Identifiers

PMID: 27178185
DOI: 10.1007/s40291-016-0203-6

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detecting Primary KIT Mutations in Presurgical Plasma of Patients with Gastrointestinal Stromal Tumor.PMID 27178185Read ↗

Detection of KIT and PDGFRA mutations in the plasma of patients with gastrointestinal stromal tumor.Semantic proximity Read ↗

Utility of Circulating Tumor DNA in the Management of Patients With GI Stromal Tumor: Analysis of 243 PatientsSemantic proximity Read ↗

Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors.Semantic proximity Read ↗

Monitoring advanced gastrointestinal stromal tumor with circulating tumor DNA.Semantic proximity Read ↗

Comprehensive targeted next‐generation sequencing approach in the molecular diagnosis of gastrointestinal stromal tumorSemantic proximity Read ↗

Genomic profiling in GIST: Implications in clinical outcome and future challenges.Semantic proximity Read ↗

Latest advances in adult gastrointestinal stromal tumors.Semantic proximity Read ↗

Clinical impact of primary and secondary KIT mutations on the efficacy of molecular-targeted therapies in gastrointestinal stromal tumors.Semantic proximity Read ↗

Kinase genotype analysis of gastric gastrointestinal stromal tumor cytology samples using targeted next-generation sequencing.Semantic proximity Read ↗

Mutational spectrum and classification of novel mutations in patients with metastatic gastrointestinal stromal tumours.Semantic proximity Read ↗

Frequent KIT mutations in human gastrointestinal stromal tumors.Semantic proximity Read ↗

Personalized Medicine in Gastrointestinal Stromal Tumor (GIST): Clinical Implications of the Somatic and Germline DNA AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.