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Article

Hotspot mutations of PIK3CA and AKT1 genes are absent in multiple myeloma.

Leukemia research - 1 Jun 2010

Ismail Said I, Mahmoud Ismail S, Msallam Mohammed M, Sughayer Maher A

Abstract excerpt

The phosphatidylinositol-3-kinases PI3K/AKT pathway regulates many growth and survival mechanisms in the cell, and it has been implicated in development and progression of many human cancers, including multiple myeloma. Recently, many reports have revealed that the PIK3CA gene which encodes the p110 catalytic subunit of PI3K kinase is mutated in many human malignancies. To investigate the oncogenic role of...

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Source

Identifiers

PMID: 20022634
DOI: 10.1016/j.leukres.2009.11.018

Genes

AKT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hotspot mutations of PIK3CA and AKT1 genes are absent in multiple myeloma.PMID 20022634Read ↗

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