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Article

Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines.

PloS one - 1 Jan 2015

Hausmann Stefan, Brandt Evelyn, Köchel Carolin, Einsele Hermann, Bargou Ralf C, Seggewiss-Bernhardt Ruth, Stühmer Thorsten

Abstract excerpt

Multiple myeloma (MM) is a generally fatal plasma cell cancer that often shows activation of the phosphoinositide 3-kinase/Akt (PI3K/Akt) pathway. Targeted pharmacologic therapies, however, have not yet progressed beyond the clinical trial stage, and given the complexity of the PI3K/Akt signalling system (e.g. multiple protein isoforms, diverse feedback regulation mechanisms, strong variability between patients)...

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Source

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Identifiers

PMID: 25837824
DOI: 10.1371/journal.pone.0122689
PMCID: PMC4383545

Genes

SGK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines.PMID 25837824Read ↗

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