Article
AKT1 and PIK3CA activating mutations in Moroccan bladder cancer patients´ biopsies and matched urine.
The Pan African medical journal - 1 Jan 2022
El Ahanidi Hajar, El Azzouzi Meryem, Arrouchi Housna, Alaoui Chaimae Hafidi, Tetou Mohammed, Bensaid Mounia, Oukabli Mohamed, Ameur Ahmed, Al Bouzidi Abderrahmane, El Mzibri Mohammed, Attaleb Mohammed
Abstract excerpt
Introduction: in cancer cells, activating mutations in PIK3CA and AKT1 genes, major players of PI3K-AKT-mTOR signalling pathway, are widely reported in many cancers and present attractive targets for the identification of new therapeutics and better cancer management. The present study was planned to evaluate the mutational status of PIK3CA and AKT1 genes in bladder cancer patients and to assess the association...
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