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Article

<i>Plasmodium falciparum var</i> gene expression is modified by host immunity

11 Dec 2009

Abstract excerpt

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a potentially important family of immune targets, which play a central role in the host-parasite interaction by binding to various host molecules. They are encoded by a diverse family of genes called var, of which there are approximately 60 copies in each parasite genome. In sub-Saharan Africa, although P. falciparum infection occurs throughout...

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PMID: 20018734
DOI: 10.1073/pnas.0907590106

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