Article
Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children.
Infection and immunity - 1 Jul 2006
Rottmann Matthias, Lavstsen Thomas, Mugasa Joseph Paschal, Kaestli Mirjam, Jensen Anja T R, Müller Dania, Theander Thor, Beck Hans-Peter
Abstract excerpt
The var gene family of Plasmodium falciparum encodes the variant surface antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 is considered an important pathogenicity factor in P. falciparum infection because it mediates cytoadherence to host cell endothelial receptors. v...
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