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Article

Virulence of Malaria Is Associated with Differential Expression of<i>Plasmodium falciparum var</i>Gene Subgroups in a Case‐Control Study

2 May 2006

Abstract excerpt

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a major pathogenicity factor in falciparum malaria that mediates cytoadherence. PfEMP1 is encoded by approximately 60 var genes per haploid genome. Most var genes are grouped into 3 subgroups: A, B, and C. Evidence is emerging that the specific expression of these subgroups has clinical significance. Using field samples from children from Papua New...

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PMID: 16652286
DOI: 10.1086/503776

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Related research

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Virulence of Malaria Is Associated with Differential Expression of<i>Plasmodium falciparum var</i>Gene Subgroups in a Case‐Control StudyPMID 16652286Read ↗

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