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Article

One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study.

Cancer causes & control : CCC - 1 Apr 2010

Van Guelpen Bethany, Dahlin Anna M, Hultdin Johan, Eklöf Vincy, Johansson Ingegerd, Henriksson Maria L, Cullman Inger, Hallmans Göran, Palmqvist Richard

Abstract excerpt

OBJECTIVE: We related prediagnostic plasma folate, vitamin B12, and total homocysteine concentrations, and the MTHFR 677C>T and 1298A>C polymorphisms, to the risk of colorectal cancer with and without the CpG island methylator phenotype (CIMP). METHODS: This was a nested case-referent study of 190 cases and double, matched referents from the large, population-based Northern Sweden Health and Disease Study. Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20012180
DOI: 10.1007/s10552-009-9484-y

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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