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Article

Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk.

Epidemiology (Cambridge, Mass.) - 1 Nov 2016

Myte Robin, Gylling Björn, Schneede Jörn, Ueland Per Magne, Häggström Jenny, Hultdin Johan, Hallmans Göran, Johansson Ingegerd, Palmqvist Richard, Van Guelpen Bethany

Abstract excerpt

BACKGROUND: Despite extensive study, the role of folate in colorectal cancer remains unclear. Research has therefore begun to address the role of other elements of the folate-methionine metabolic cycles. This study investigated factors other than folate involved in one-carbon metabolism, i.e., choline, betaine, dimethylglycine, sarcosine, and methionine and relevant polymorphisms, in relation to the risk of...

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PMID: 27367522
DOI: 10.1097/EDE.0000000000000529

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