Bi-directional SIFT predicts a subset of activating mutations.

Abstract excerpt

Advancements in sequencing technologies have empowered recent efforts to identify polymorphisms and mutations on a global scale. The large number of variations and mutations found in these projects requires high-throughput tools to identify those that are most likely to have an impact on function. Numerous computational tools exist for predicting which mutations are likely to be functional, but none that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computational Biology
• Share to Databases, Protein
• Share to Models, Molecular