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Post‐mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms

22 Jun 2019

Abstract excerpt

Over the last few decades, several common single nucleotide polymorphisms (SNPs) have been identified that correlate with clinical outcome in multiple sclerosis (MS), but the pathogenic mechanisms underlying the clinical effects of these SNPs are unknown. This is in part because of the difficulty in the functional translation of genotype into disease-relevant mechanisms. Building on our recent work showing the...

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PMID: 31228212
DOI: 10.1111/bpa.12760

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