Article
Genetic correlations of brain lesion distribution in multiple sclerosis: an exploratory study.
AJNR. American journal of neuroradiology - 1 Apr 2011
Sombekke M H, Vellinga M M, Uitdehaag B M J, Barkhof F, Polman C H, Arteta D, Tejedor D, Martinez A, Crusius J B A, Peña A S, Geurts J J G, Vrenken H
Abstract excerpt
BACKGROUND AND PURPOSE: In MS, the total brain lesion volume and spatial distribution of lesions across the brain vary widely among individual patients. We hypothesized that spatial distribution may be partially driven by genetic predisposition, and we aimed to explore relations among candidate genes and the spatial distribution of white matter brain lesions in MS. MATERIAL AND METHODS: Genotypes of 69 SNPs in...
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