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Article

Interaction effect of D4 dopamine receptor gene and serotonin transporter promoter polymorphism on the cortisol stress response.

Behavioral neuroscience - 1 Dec 2009

Armbruster D, Mueller A, Moser D A, Lesch K P, Brocke B, Kirschbaum C

Abstract excerpt

Genetic variation of the serotonin transporter (SCL6A4, 5-HTT) has been associated with fear- and anxiety-related behaviors, while a polymorphism in exon III of the D4 dopamine receptor gene (DRD4) has been linked to novelty seeking. The dopaminergic and the serotonergic neurotransmitter system have been found to modulate the amygdala-connected circuitries that are crucial in emotional modulation and response to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20001112
DOI: 10.1037/a0017615

Genes

DRD4
HTT

Provenance

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