Article
Gene-environment interactions predict cortisol responses after acute stress: implications for the etiology of depression.
Psychoneuroendocrinology - 1 Oct 2009
Alexander Nina, Kuepper Yvonne, Schmitz Anja, Osinsky Roman, Kozyra Eva, Hennig Juergen
Abstract excerpt
BACKGROUND: Growing evidence suggests that the serotonin transporter polymorphism (5-HTTLPR) interacts with adverse environmental influences to produce an increased risk for the development of depression while the underlying mechanisms of this association remain largely unexplored. As one potential intermediate phenotype, we investigated alterations of hypothalamic-pituitary-adrenal (HPA) axis responses to stress...
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