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Article

Genetic variants within the dopaminergic system interact to modulate endocrine stress reactivity and recovery.

Behavioural brain research - 1 Jan 2011

Alexander Nina, Osinsky Roman, Mueller Eva, Schmitz Anja, Guenthert Sarah, Kuepper Yvonne, Hennig Juergen

Abstract excerpt

Catecholamines modulate endocrine stress reactivity by affecting regulatory influences of extra-hypothalamic brain structures on hypothalamus-pituitary-adrenal (HPA)-axis. Therefore, we aimed to investigate combined effects of functional allelic variations that affect dopamine availability in both cortical (COMT Val¹⁵⁸Met polymorphism) and subcortical (DAT1 VNTR) brain regions on HPA-axis reactivity to...

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Share to Catechol O-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20620172
DOI: 10.1016/j.bbr.2010.07.003

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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