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Article

Sex-specific association between the 5-HTT gene-linked polymorphic region and basal cortisol secretion.

Psychoneuroendocrinology - 1 Aug 2009

Wüst Stefan, Kumsta Robert, Treutlein Jens, Frank Josef, Entringer Sonja, Schulze Thomas G, Rietschel Marcella

Abstract excerpt

OBJECTIVE: A key regulator of serotonergic neurotransmission is the serotonin transporter (5-HTT) and a common 5HTT gene promoter polymorphism, termed 5HTTLPR, is associated with phenotypes related to anxiety and depression. Furthermore, the serotonergic system influences hypothalamus-pituitary-adrenal (HPA) axis activity, which, in turn, is related to psychiatric diseases. METHODS: To explore the association...

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Source

Identifiers

PMID: 19249159
DOI: 10.1016/j.psyneuen.2009.01.011

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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