Article
Isolation of a mutant of Chinese hamster ovary cells with defective secretion of a subset of secretory proteins.
Somatic cell and molecular genetics - 1 Jan 1991
Kaiden A, Krag S S
Abstract excerpt
The secretory pathway of mammalian cells involves a complex sequence of steps beginning with the translation and translocation of proteins across the rough endoplasmic reticulum membrane followed by their transport through a variety of intracellular compartments. Understanding the cellular mechanisms involved in protein transport would be facilitated by the application of somatic cell genetics techniques....
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