Article
Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.
Molecular and cellular biology - 1 Dec 1990
Chavrier P, Vingron M, Sander C, Simons K, Zerial M
Abstract excerpt
Molecular analysis of Saccharomyces cerevisiae secretion mutants has led to the identification of two Ras-like GTP-binding proteins, Ypt1p and Sec4p, which are essential for transport along the exocytic route. To study the regulation of membrane traffic in epithelial cells, a set of 11 clones encoding proteins similar to the YPT1/SEC4 products were isolated from an MDCK (Madin-Darby canine kidney) cell cDNA...
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