Article
Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiae.
Journal of cell science - 1 Mar 1992
Chow T Y, Ash J J, Dignard D, Thomas D Y
Abstract excerpt
Utilizing a screening method designed for the identification of genes involved with enhanced protein secretion in Saccharomyces cerevisiae we identified a gene, which we named PSE-1 (Protein Secretion Enhancer). Overexpression of PSE-1 in a multi-copy plasmid, as shown by Northern hybridization, gave a fourfold enhancement in total protein secretion. The repertoire of proteins that are found to be secreted in...
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