Article
Dominant negative alleles of SEC10 reveal distinct domains involved in secretion and morphogenesis in yeast.
Molecular biology of the cell - 1 Jul 1998
Roth D, Guo W, Novick P
Abstract excerpt
The accurate targeting of secretory vesicles to distinct sites on the plasma membrane is necessary to achieve polarized growth and to establish specialized domains at the surface of eukaryotic cells. Members of a protein complex required for exocytosis, the exocyst, have been localized to regions of active secretion in the budding yeast Saccharomyces cerevisiae where they may function to specify sites on the...
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