Article
Expression profiles of schizophrenia susceptibility genes during human prefrontal cortical development.
Journal of psychiatry & neuroscience : JPN - 1 Nov 2009
Choi Kwang H, Zepp Megan E, Higgs Brandon W, Weickert Cynthia S, Webster Maree J
Abstract excerpt
BACKGROUND: Disruption in normal development of the human prefrontal cortex (PFC) may lead to cognitive dysfunction that manifests in individuals with schizophrenia. We sought to identify genes associated with age that are implicated in schizophrenia. METHODS: We generated genome-wide expression profiles for the PFCs of humans ranging in age from 1 month to 49 years using the Affymetrix HG-U133 plus 2.0...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
