Article

Developmental expression of risk genes implicates the age of onset for neuropsychiatric disorders

2025-08-28

Abstract excerpt

The functional effects of genetic variants associated with complex diseases exhibit pronounced spatiotemporal specificity. Although spatially resolved studies have advanced, their temporal dynamics remain poorly characterized. Here, we present an analytical framework integrating developmental gene expression with genome-wide association studies to decipher age-specific windows during which genetic variants exert t...

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Literature Corpus work: 7a881170-e962-5e6b-8761-48d5008ee8be
DOI: 10.1101/2025.08.27.672343

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