Article
Intrahost and interhost variability of the HIV type 1 nef gene in Brazilian children.
AIDS research and human retroviruses - 1 Nov 2009
Cavalieri Elizabeth, Florido Camila, Leal Elcio, Machado Daisy Maria, Camargo Michelle, Diaz Ricardo S, Janini Luiz Mario
Abstract excerpt
Many aspects of HIV-1 pathogenesis are affected by Nef protein activity, and efforts have been made to study variation in the nef gene and how that variation relates to disease outcome. We studied the genetic diversity of the nef gene in distinct clones obtained from the same patient (intrahost) and in sequences obtained from different hosts (interhost). The set of sequences analyzed was obtained from...
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